Lamin A/C anticorps
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- Antigène Voir toutes Lamin A/C (LMNA) Anticorps
- Lamin A/C (LMNA)
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Reactivité
- Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Lamin A/C est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Mouse monoclonal to Lamin A.
- Specificité
- Lamin A Monoclonal Antibody detects endogenous levels of Lamin A protein.
- Attributs du produit
- Mouse Monoclonal to Lamin A.
- Purification
- Affinity purification
- Immunogène
- Purified recombinant fragment of human Lamin A expressed in E. Coli.
- Clone
- 4E7
- Isotype
- IgG1
- Top Product
- Discover our top product LMNA Anticorps primaire
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- Indications d'application
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WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000 - Commentaires
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In the arteries, prelamin-A/C accumulation is not observed in young healthy vessels but is prevalent in medial vascular smooth muscle cells (VSMCs) from aged individuals and in atherosclerotic lesions, where it often colocalizes with senescent and degenerate VSMCs. Prelamin-A/C expression increases with age and disease. In normal aging, the accumulation of prelamin-A/C is caused in part by the down-regulation of ZMPSTE24/FACE1 in response to oxidative stress.
- Restrictions
- For Research Use only
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- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- Lamin A/C (LMNA)
- Autre désignation
- Lamin A (LMNA Produits)
- Synonymes
- anticorps CDCD1, anticorps CDDC, anticorps CMD1A, anticorps CMT2B1, anticorps EMD2, anticorps FPL, anticorps FPLD, anticorps FPLD2, anticorps HGPS, anticorps IDC, anticorps LDP1, anticorps LFP, anticorps LGMD1B, anticorps LMN1, anticorps LMNC, anticorps LMNL1, anticorps PRO1, anticorps Dhe, anticorps 2459, anticorps 74/76, anticorps CG6944, anticorps D5, anticorps DM[[O]], anticorps Dm, anticorps Dm(0), anticorps Dm0, anticorps Dm1, anticorps Dm2, anticorps DmLamin, anticorps DmO, anticorps Dm[[0]], anticorps Dm[[1]], anticorps Dm[[2]], anticorps Dm[[mit]], anticorps Dm[[o]], anticorps Dmel\\CG6944, anticorps Dmo, anticorps LAM, anticorps Lam Dm[[0]], anticorps Lam(Dm0), anticorps LamDm[[0]], anticorps LamDm[[o]], anticorps Lam[[Dm0]], anticorps Lamin Dm[[0]], anticorps jf27, anticorps l(2)04643, anticorps l(2)25Ec, anticorps l(2)gdh-7, anticorps l(2)gdh7, anticorps l(2)jf27, anticorps lam, anticorps lamDm0, anticorps lamDm[[0]], anticorps lamin, anticorps lamin Dm0, anticorps lamin Dm[[0]], anticorps misg, anticorps nlam, anticorps cb948, anticorps fk66d12, anticorps wu:fk66d12, anticorps lmna-A, anticorps fpl, anticorps idc, anticorps lfp, anticorps cddc, anticorps emd2, anticorps fpld, anticorps hgps, anticorps ldp1, anticorps lmn1, anticorps lmnc, anticorps pro1, anticorps cdcd1, anticorps cmd1a, anticorps cmt2b1, anticorps lgmd1b, anticorps Lamin-A, anticorps lamin-L(III)-like, anticorps lamin A/C, anticorps lamin A, anticorps Lamin, anticorps lamin A/C L homeolog, anticorps lamin-L(III)-like, anticorps LMNA, anticorps Lmna, anticorps Lam, anticorps lmna, anticorps lmna.L, anticorps LMINA
- ID gène
- 4000
- UniProt
- P02545
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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