PICALM anticorps

N° du produit ABIN4904757

Détail du produit anti-PICALM anticorps

Antigène: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PICALM est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification: Affinity purification

Immunogène: Recombinant protein of human PICALM.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur PICALM

Antigène: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Autre désignation: PICALM (PICALM Produits)

Synonymes: anticorps LAP-3, anticorps PEPS, anticorps CALM, anticorps CLTH, anticorps LAP, anticorps PAP180, anticorps fit-1, anticorps fit1, anticorps mKIAA4114, anticorps Calm, anticorps leucine aminopeptidase 3, anticorps phosphatidylinositol binding clathrin assembly protein, anticorps si:ch211-200p22.4, anticorps LAP3, anticorps PICALM, anticorps Picalm, anticorps si:ch211-200p22.4

ID gène: 8301

UniProt: Q13492

Pathways: Synaptic Membrane