RELB anticorps

N° du produit ABIN4904989

Détail du produit anti-RELB anticorps

Antigène: RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RELB est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: RelB, also known as I-Rel, is a member of the Rel transcription factor family which also include, RelA-p65, c-Rel, NF-kB1 p100/52 and NF-kB2 p105/50. Unlike other Rel-related protein, RelB does not bind to DNA or to inhibitor IkB, but is instead sequestered in the cytoplasm by precursor p100. Once p100 is processed, the p52/RelB complex translocates into the nucleus. RelB is also the transcription factor that has been associated most directly with dendritic cells (DCs) differentiation and function. It is upregulated and translocated into the nuclei of DC in response to various stimuli. RelB is also essential for generating a specific DC subset (CD11c +/CD11b +/CD8 -/Dec205 -) from hematopoietic stem cells.

Purification: Affinity purification

Immunogène: Recombinant protein of human RELB.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur RELB

Antigène: RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

Autre désignation: RELB (RELB Produits)

Synonymes: anticorps shep, anticorps I-REL, anticorps IREL, anticorps REL-B, anticorps XRelB, anticorps relb-A, anticorps GC-rich, anticorps avian reticuloendotheliosis viral (v-rel) oncogene related B, anticorps RELB proto-oncogene, NF-kB subunit, anticorps v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog, anticorps Relb, anticorps RELB, anticorps relb.S

ID gène: 5971

UniProt: Q01201

Pathways: Signalisation NF-kappaB, Signalisation RTK