Integrin-Linked Kinase (ILK) anticorps

Détails pour le produit réf. ABIN4951471
Antigène
  • CG10504
  • CT29478
  • DmILK
  • Dmel\\CG10504
  • ILK
  • ilk
  • l(3)78Ca
  • p59
  • AA511515
  • ESTM24
  • zgc:65842
  • ILK-1
  • ILK-2
  • P59
  • p59ILK
  • Integrin linked kinase
  • integrin linked kinase
  • integrin linked kinase S homeolog
  • integrin-linked protein kinase
  • integrin-linked kinase
  • Ilk
  • ILK
  • ilk.S
  • CpipJ_CPIJ016644
  • Bm1_20815
  • Tsp_07213
  • Tsp_07224
  • Tsp_15354
  • ilk
Reactivité
Humain, Souris, Rat (Rattus)
265
109
106
4
2
1
1
1
1
1
1
1
Hôte
Lapin
249
10
7
Clonalité
Polyclonal
Conjugué
Inconjugué
20
17
16
11
11
11
7
7
7
7
7
7
3
3
3
3
3
Application
Western Blotting (WB)
157
139
110
39
26
21
13
7
6
5
2
2
2
2
1
Options
Immunogène Amino acids M1-H203 from the human protein were used as the immunogen for the Integrin linked kinase antibody.
Isotype IgG
Purification Antigen affinity
Antigène
Autre désignation Integrin linked kinase (ILK) (ILK Antibody Extrait)
Sujet ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.
UniProt Q13418
Pathways Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
Indications d'application Optimal dilution of the Integrin linked kinase antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the Integrin linked kinase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Integrin-Linked Kinase (ILK) antibody (ABIN4951471) Western blot testing of 1) rat lung, 2) mouse liver and 3) human HeLa lysate with Int...
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