Mesothelin anticorps (AA 308-576)

N° du produit ABIN4951714

Détail du produit anti-Mesothelin anticorps

Antigène: Mesothelin (MSLN)

Épitope: AA 308-576

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Amino acids 308-576 of mouse Mesothelin were used as the immunogen for the Mesothelin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Mesothelin antibody should be determined by the researcher.\. IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Mesothelin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: Mesothelin (MSLN Produits)

Synonymes: anticorps MPF, anticorps SMRP, anticorps MSLN, anticorps mesothelin, anticorps MSLN, anticorps Msln, anticorps LOC611363, anticorps LOC100524016

Sujet: Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

UniProt: Q61468

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process