Mesothelin anticorps (MSLN) (AA 308-576)

Details for Product anti-MSLN Antibody No. ABIN4951714
Antigène
  • MPF
  • SMRP
  • MSLN
  • mesothelin
  • MSLN
  • Msln
  • LOC611363
  • LOC100524016
Épitope
AA 308-576
16
10
7
7
5
4
4
4
4
4
4
4
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Souris
149
32
9
2
2
2
2
1
1
1
Hôte
Lapin
116
41
7
4
1
Clonalité
Polyclonal
Conjugué
Cet anticorp Mesothelin est non-conjugé
15
9
9
3
3
3
3
3
3
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
107
71
43
21
20
13
8
7
6
6
4
4
3
2
2
2
2
1
1
Options
Immunogène Amino acids 308-576 of mouse Mesothelin were used as the immunogen for the Mesothelin antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others Mesothelin products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Mesothelin (MSLN Antibody Extrait)
Sujet Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.
UniProt Q61468
Pathways EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
Indications d'application Optimal dilution of the Mesothelin antibody should be determined by the researcher.\. IHC (Paraffin): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the Mesothelin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Mesothelin (MSLN) (AA 308-576) antibody (ABIN4951714) IHC testing of FFPE mouse lung with Mesothelin antibody. HIER: Boil the paraffin sect...
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