RAD51C anticorps

N° du produit ABIN4952350

Détail du produit anti-RAD51C anticorps

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51C est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids IQHLQLIAEKHKGEEHRKALEDFTLDNILSH of human RAD51C were used as the immunogen for the RAD51C antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RAD51C antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RAD51C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RAD51C

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Autre désignation: RAD51C (RAD51C Produits)

Synonymes: anticorps RGD1563765, anticorps CG2412, anticorps Dm CG2412, anticorps Dmel\\CG2412, anticorps zgc:101596, anticorps RAD51C, anticorps Rad51c, anticorps ATRAD51C, anticorps F4L23.21, anticorps RAS associated with diabetes protein 51C, anticorps R51H3, anticorps Rad51l2, anticorps BROVCA3, anticorps FANCO, anticorps RAD51L2, anticorps RAD51 paralog C, anticorps Rad51 recombinase D, anticorps Rad51 DNA recombinase 3, anticorps RAD51C protein, anticorps RAD51 homolog C, anticorps RAS associated with diabetes protein 51C, anticorps RAD51C, anticorps Rad51c, anticorps Rad51D, anticorps rad51c

Sujet: RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

UniProt: O43502

Pathways: Réparation de l'ADN