TRPM5
Reactivité: Humain, Souris, Rat
WB, IF (p)
Hôte: Lapin
Polyclonal
Alexa Fluor 350
Indications d'application
Optimal dilution of the TRPM5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
-20 °C
Stockage commentaire
After reconstitution, the TRPM5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Antigène
TRPM5
(Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))
anticorps LTRPC5, anticorps MTR1, anticorps 9430099A16Rik, anticorps LTrpC-5, anticorps Ltrpc5, anticorps Mtr1, anticorps transient receptor potential cation channel subfamily M member 5, anticorps transient receptor potential cation channel, subfamily M, member 5, anticorps TRPM5, anticorps Trpm5, anticorps trpm5
Sujet
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a protein that in humans is encoded by the TRPM5 gene. This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.