PKC alpha anticorps

N° du produit ABIN4953283

L’anticorps Souris Monoclonal anti-PKC alpha a été validé pour WB. Il convient pour détecter PKC alpha dans des échantillons de Rat et Primate.

Aperçu rapide pour PKC alpha anticorps (ABIN4953283)

Antigène: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Reactivité: Rat, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PKC alpha est non-conjugé

Application: Western Blotting (WB)

Clone: 3G11-G11-G11

Détail du produit anti-PKC alpha anticorps

Réactivité croisée (Details): Expected species reactivity: Human

Purification: Protein G affinity

Immunogène: A synthetic PKC alpha/aPKC peptide was used as the immunogen for the PKC alpha antibody.

Isotype: IgG2a

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Stock: -20 °C

Stockage commentaire: Store the PKC alpha antibody at -20°C.

Détails sur PKC alpha

Antigène: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Autre désignation: PRKCA / PKC alpha

Sujet: This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

UniProt: P17252

Pathways: Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling