CYP1A2 anticorps (AA 255-282)

N° du produit ABIN3030672

Détail du produit anti-CYP1A2 anticorps

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Épitope: AA 255-282

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP1A2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 255-282 from the human protein was used as the immunogen for this CYP1A2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CYP1A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CYP1A2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CYP1A2

Antigène: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Autre désignation: CYP1A2 (CYP1A2 Produits)

Synonymes: anticorps CP12, anticorps P3-450, anticorps P450(PA), anticorps CYP1A2, anticorps CYPIA2, anticorps P450-PM4, anticorps Cyp1a1, anticorps P450-3, anticorps CYPD45, anticorps P-450d, anticorps RATCYPD45, anticorps CYP1A5, anticorps CP450, anticorps CYP-IA2, anticorps cytochrome P450 family 1 subfamily A member 2, anticorps cytochrome P450 1A2, anticorps cytochrome P450 LM4, anticorps cytochrome P450, family 1, subfamily A, polypeptide 2, anticorps cytochrome P450, family 1, subfamily a, polypeptide 2, anticorps cytochrome P450 1A2-like, anticorps CYP1A2, anticorps LOC100328937, anticorps Cyp1a2, anticorps VDBG_06455, anticorps LOC101825565, anticorps LOC102130662

Sujet: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, CYP1A2 is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. [UniProt]

UniProt: P05177