MAPK11 anticorps (AA 334-359)

N° du produit ABIN3031829

L’anticorps anti-MAPK11 Polyclonal Lapin est utilisé pour la détection de MAPK11 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour MAPK11 anticorps (AA 334-359) (ABIN3031829)

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK11 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MAPK11 anticorps

Épitope: AA 334-359

Fonction: MAPK11 Antibody

Purification: Purified

Immunogène: A portion of amino acids 334-359 from the human protein was used as the immunogen for this MAPK11 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MAPK11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MAPK11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MAPK11

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Autre désignation: MAPK11

Sujet: P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.

UniProt: Q15759

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins