XRCC1 anticorps (AA 407-435)

N° du produit ABIN3029645

Détail du produit anti-XRCC1 anticorps

Antigène: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Épitope: AA 407-435

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XRCC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 407-435 from the human protein was used as the immunogen for this XRCC1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the XRCC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the XRCC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur XRCC1

Antigène: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Autre désignation: XRCC1 (XRCC1 Produits)

Synonymes: anticorps xrcc1, anticorps MGC80909, anticorps XRCC1, anticorps rcc, anticorps RCC, anticorps Xrcc-1, anticorps X-ray repair complementing defective repair in Chinese hamster cells 1, anticorps X-ray repair cross complementing 1, anticorps xrcc1, anticorps XRCC1, anticorps Xrcc1

Sujet: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

UniProt: P18887

Pathways: Réparation de l'ADN