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VEGFR2/CD309 anticorps
VEGFR2
Reactivité: Humain, Souris, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-VEGFR2/CD309 anticorps
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Antigène
Voir toutes VEGFR2/CD309 (VEGFR2) Anticorps
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Reactivité
Toutes les réactivités sur VEGFR2/CD309 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur VEGFR2/CD309 Anticorps
Lapin
Clonalité
Toutes les clonalités sur VEGFR2/CD309 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers VEGFR2/CD309 Anticorps
Cet anticorp VEGFR2/CD309 est non-conjugé
Application
Tous les applications à travers VEGFR2/CD309 Anticorps.
Western Blotting (WB)
Specificité
This antibody detects endogenous levels of Flk-1 protein.
Réactivité croisée (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography using epitope-specific immunogen
Pureté
> 95 % (by SDS-PAGE)
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Détails sur VEGFR2/CD309
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Antigène
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Autre désignation
CD309 / VEGFR-2 / Flk-1 (VEGFR2 Produits )
Synonymes
anticorps CD309, anticorps FLK1, anticorps VEGFR, anticorps VEGFR2, anticorps 6130401C07, anticorps Flk-1, anticorps Flk1, anticorps Krd-1, anticorps Ly73, anticorps VEGFR-2, anticorps sVEGFR-2, anticorps Vegfr-2, anticorps FLK-1, anticorps flk-1, anticorps vegfr-2, anticorps KDR, anticorps FLK/KDR, anticorps flk1, anticorps flk1b, anticorps kdrb, anticorps si:busm1-205d10.1, anticorps si:ch211-254j6.1, anticorps si:ch211-278f21.4, anticorps wu:fc31a09, anticorps fk52c05, anticorps flk, anticorps kdr, anticorps kdra, anticorps vegfr2, anticorps vegfr4, anticorps vegr2, anticorps wu:fk52c05, anticorps kinase insert domain receptor, anticorps kinase insert domain protein receptor, anticorps vascular endothelial growth factor receptor kdr-like, anticorps kinase insert domain receptor (a type III receptor tyrosine kinase), anticorps kinase insert domain receptor like, anticorps KDR, anticorps Kdr, anticorps LOC100136647, anticorps kdr, anticorps kdrl
Sujet
Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2
Poids moléculaire
approx. 150, 210 kDa
ID gène
3791
NCBI Accession
NP_002244
UniProt
P35968
Pathways
Signalisation RTK , Glycosaminoglycan Metabolic Process , Signaling Events mediated by VEGFR1 and VEGFR2 , Growth Factor Binding , Regulation of long-term Neuronal Synaptic Plasticity , VEGF Signaling
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