MKL1 anticorps

N° du produit ABIN498351

Détail du produit anti-MKL1 anticorps

Antigène: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MKL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of MRTF-A protein. (region surrounding His11)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MKL1

Antigène: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Abstract: MKL1 Produits

Synonymes: anticorps MKL1, anticorps BSAC, anticorps MAL, anticorps MRTF-A, anticorps Mrtf-a, anticorps mrtf-a, anticorps mrtfa, anticorps AI852829, anticorps AMKL, anticorps AW743281, anticorps AW821984, anticorps Bsac, anticorps Mal, anticorps Mrtf-A, anticorps megakaryoblastic leukemia (translocation) 1, anticorps megakaryoblastic leukemia 1 protein, anticorps megakaryoblastic leukemia (translocation) 1 S homeolog, anticorps MKL (megakaryoblastic leukemia)/myocardin-like 1, anticorps MKL1, anticorps mkl1, anticorps Mkl1, anticorps mkl1.S

Sujet: Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factor A (MRTF-A), also known as MKL1, interacts with SRF and stimulates its transcriptional activity.Synonyms: Basic SAP coiled-coil transcription activator, Bsac, MKL, Megakaryoblastic leukemia 1 protein homolog, Mkl1, Myocardin-related transcription factor A

Poids moléculaire: approx. 99 kDa

ID gène: 57591

NCBI Accession: NP_065882

UniProt: Q969V6