FOXO4 anticorps

N° du produit ABIN498929

Détail du produit anti-FOXO4 anticorps

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO4 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of FOXO4 protein. (region surrounding Ser203)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FOXO4

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Autre désignation: FOXO4 / AFX1 / MLLT7 (FOXO4 Produits)

Synonymes: anticorps FOXO4, anticorps foxo4, anticorps AFX, anticorps AFX1, anticorps MLLT7, anticorps Afxh, anticorps Mllt7, anticorps afx, anticorps RGD1561201, anticorps forkhead box O4, anticorps forkhead box O4 L homeolog, anticorps FOXO4, anticorps foxo4.L, anticorps Foxo4

Sujet: FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulinresponse elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4

Poids moléculaire: approx. 55, 70 kDa

ID gène: 4303

NCBI Accession: NP_005929

UniProt: P98177

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation