AP2M1 anticorps (pThr156) (Alexa Fluor 680)
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- Antigène Voir toutes AP2M1 Anticorps
- AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
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Épitope
- pThr156
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AP2M1 est conjugé à/à la Alexa Fluor 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Sheep,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human AP2M1 around the phosphorylation site of Thr156
- Isotype
- IgG
- Top Product
- Discover our top product AP2M1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
- Autre désignation
- AP2M1 (AP2M1 Produits)
- Synonymes
- anticorps AP50, anticorps CLAPM1, anticorps mu2, anticorps Ap50, anticorps Clapm1, anticorps cb34, anticorps Ap2m1, anticorps dpy-23, anticorps sb:cb34, anticorps zgc:55711, anticorps zgc:85653, anticorps wu:fa97a10, anticorps ap2m1-a, anticorps ap2m1, anticorps zgc:56643, anticorps AP2M1, anticorps adaptor related protein complex 2 mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, a, anticorps adaptor related protein complex 2 mu 1 subunit L homeolog, anticorps adaptor-related protein complex 2, mu 1 subunit, b, anticorps AP-2 complex subunit mu-1, anticorps clathrin coat assembly protein AP50, anticorps clathrin coat assembly protein ap50, anticorps AP2M1, anticorps Ap2m1, anticorps ap2m1a, anticorps ap2m1.L, anticorps ap2m1b, anticorps ap2m1, anticorps cgd8_950, anticorps PY06523, anticorps PVX_118455, anticorps PVX_123590, anticorps CpipJ_CPIJ003697
- Sujet
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Synonyms: AP2M1 phospho T156, p-AP2M1phospho T156, Adaptin mu 1, Clathrin coat associated protein AP50, Adapter-related protein complex 2 mu subunit, Adaptin-mu2, Adaptor protein complex AP 2 subunit mu, Adaptor protein complex AP-2 subunit mu, Adaptor related protein complex 2 mu 1 subunit, AP 2 mu 2 chain, AP-2 complex subunit mu, AP-2 mu chain, Ap2m1, AP2M1_HUMAN, AP50, CLAPM1, Clathrin adaptor complex AP2 mu subunit, Clathrin assembly protein complex 2 medium chain, Clathrin associated/assembly/adaptor protein medium 1, Clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, HA2 50 kDa subunit, mu2 antibody, Plasma membrane adaptor AP-2 50 kDa protein.
Background: Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
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