FOXA2 anticorps (AA 201-300) (AbBy Fluor® 680)
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- Antigène Voir toutes FOXA2 Anticorps
- FOXA2 (Forkhead Box A2 (FOXA2))
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Épitope
- AA 201-300
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FOXA2 est conjugé à/à la AbBy Fluor® 680
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human HNF 3 beta
- Isotype
- IgG
- Top Product
- Discover our top product FOXA2 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FOXA2 (Forkhead Box A2 (FOXA2))
- Autre désignation
- FOXA2/HNF 3beta (FOXA2 Produits)
- Synonymes
- anticorps hnf3b, anticorps tcf3b, anticorps hnf3beta, anticorps hnf3-beta, anticorps FOXA2, anticorps HNF3B, anticorps TCF3B, anticorps HNF-3B, anticorps ax, anticorps axl, anticorps fkd1, anticorps ik:tdsubc_2g8, anticorps tdsubc_2g8, anticorps wu:fe05g04, anticorps xx:tdsubc_2g8, anticorps FoxA2-A, anticorps FoxA2a, anticorps xFD-3, anticorps xbeta-1, anticorps HNF-3b, anticorps HNF3-beta, anticorps HNF3beta, anticorps Hnf-3b, anticorps Hnf3b, anticorps Tcf-3b, anticorps Tcf3b, anticorps HNF-3BETA, anticorps forkhead box A2, anticorps forkhead box A2 L homeolog, anticorps foxa2, anticorps FOXA2, anticorps foxa2.L, anticorps Foxa2
- Sujet
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Synonyms: HNF3B, TCF3B, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, Forkhead box protein A2, Transcription factor 3B, TCF-3B, FOXA2
Background: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs, FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
- ID gène
- 3170
- UniProt
- Q9Y261
- Pathways
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
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