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Histone 3 anticorps (acLys10, pSer11) (AbBy Fluor® 680)

H3 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal AbBy Fluor® 680
N° du produit ABIN5004674
  • Antigène Voir toutes Histone 3 (H3) Anticorps
    Histone 3 (H3)
    Épitope
    • 60
    • 47
    • 44
    • 44
    • 41
    • 36
    • 35
    • 35
    • 34
    • 34
    • 34
    • 32
    • 29
    • 29
    • 28
    • 27
    • 26
    • 25
    • 22
    • 22
    • 22
    • 22
    • 20
    • 18
    • 18
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 14
    • 13
    • 13
    • 12
    • 12
    • 12
    • 11
    • 11
    • 11
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    acLys10, pSer11
    Reactivité
    • 1376
    • 939
    • 860
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 26
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 1183
    • 246
    • 12
    • 4
    Lapin
    Clonalité
    • 1108
    • 336
    • 1
    Polyclonal
    Conjugué
    • 798
    • 81
    • 48
    • 47
    • 47
    • 47
    • 46
    • 45
    • 34
    • 33
    • 22
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 16
    • 16
    • 16
    • 12
    • 1
    Cet anticorp Histone 3 est conjugé à/à la AbBy Fluor® 680
    Application
    • 1034
    • 402
    • 373
    • 311
    • 240
    • 188
    • 175
    • 171
    • 163
    • 151
    • 137
    • 127
    • 117
    • 48
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Cow,Pig,Rabbit,Drosophila
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11)
    Isotype
    IgG
    Top Product
    Discover our top product H3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Histone 3 (H3)
    Autre désignation
    Histone H3 (H3 Produits)
    Synonymes
    anticorps H-3, anticorps histocompatibility 3, anticorps H3
    Sujet

    Synonyms: H3 histone family member E pseudogene, H3F3, HIST3H3, Histone H3 3 pseudogene.

    Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

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