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Nicastrin anticorps (AA 21-120) (Alexa Fluor 680)

NCSTN Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 680

N° du produit ABIN5007635

Fiche de données

Antigène Voir toutes Nicastrin (NCSTN) Anticorps

Nicastrin (NCSTN)
Épitope
14

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 21-120
Reactivité
39

33

23

6

6

6

1

1

1
Souris
Hôte
51

3
Lapin
Anticorps secondaires appropriés
Clonalité
43

11
Polyclonal
Conjugué
22

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp Nicastrin est conjugé à/à la Alexa Fluor 680
Application
40

12

12

9

7

5

4

3

3

2

2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée

Souris

Homologie

Human,Rat,Cow,Pig,Horse,Chicken

Purification

Purified by Protein A.

Immunogène

KLH conjugated synthetic peptide derived from human Nicastrin

Isotype

IgG

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Indications d'application

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption

12 months
Antigène

Nicastrin (NCSTN)

Autre désignation

Nicastrin (NCSTN Produits)

Synonymes

anticorps CG7012, anticorps Dmel\\CG7012, anticorps Nct, anticorps Nic, anticorps S5A, anticorps ST96B, anticorps agro, anticorps dNct, anticorps nic, anticorps NCSTN, anticorps DKFZp469O2418, anticorps APH2, anticorps 9430068N19Rik, anticorps AA727311, anticorps Aph2, anticorps D1Dau13e, anticorps Kiaa0253, anticorps mKIAA0253, anticorps nicastrin, anticorps Nicastrin, anticorps NCSTN, anticorps nct, anticorps ncstn, anticorps CpipJ_CPIJ001617, anticorps Ncstn, anticorps aph-2

Sujet

Synonyms: ATAG1874, Nicastrin, NCSTN, KIAA0253, UNQ1874/PRO4317
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

ID gène

23385

UniProt

Q92542

Pathways

Signalisation Notch, Neurotrophin Signaling Pathway