TCF3 anticorps (N-Term)

N° du produit ABIN500879

Détail du produit anti-TCF3 anticorps

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: TCF3 antibody was raised against a 17 amino acid peptide near the amino terminus of human TCF3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur TCF3

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Autre désignation: TCF3 / E2A (TCF3 Produits)

Synonymes: anticorps E2A, anticorps E47, anticorps ITF1, anticorps TCF-3, anticorps VDIR, anticorps bHLHb21, anticorps tcf3a, anticorps zgc:113045, anticorps A1, anticorps AA408400, anticorps ALF2, anticorps AW209082, anticorps E12, anticorps E12/E47, anticorps ME2, anticorps Pan1, anticorps Pan2, anticorps Tcfe2a, anticorps bhlhb21, anticorps e2a, anticorps itf1, anticorps tcfe2a, anticorps vdir, anticorps xtcf-3, anticorps xtcf3, anticorps G12, anticorps TCF7L1, anticorps XE3, anticorps transcription factor 3, anticorps transcription factor 3b, anticorps transcription factor 3 L homeolog, anticorps transcription factor E2a, anticorps TCF3, anticorps tcf3b, anticorps Tcf3, anticorps tcf3.L, anticorps tcfe2a

Sujet: The TCF3 gene, also called E2A, encodes two basic helix-loop-helix (bHLH) transcription factors, E12 and E47, through alternative splicing. These transcription factors are involved in mediating canonical Wnt signaling, which is very important in a diverse array of cellular functions such as stem cell proliferation, self-renewal, activation, fate determination, differentiation and aging and senescence. They bind beta-catenin and can act as transcriptional activators or repressors for Wnt target genes, and have been shown to regulate specific target genes during CNS development downstream of Wnt signaling. TCF3/Lef complexes are also known to play key roles in controlling cell fate lineages in multipotent skin stem cells.Synonyms: ITF-1, ITF1, Immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, Kappa-E2-binding factor, TCF-3, Transcription factor 3, Transcription factor E2-alpha, Transcription factor ITF-1

ID gène: 6929

NCBI Accession: NP_003191

Pathways: Signalisation WNT, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response