S100A8 anticorps
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- Antigène Voir toutes S100A8 Anticorps
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp S100A8 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Protein G Chromatography
- Immunogène
- A full length human S100A8 protein was used as the immunogen for this antibody.
- Clone
- ABM4G30
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product S100A8 Anticorps primaire
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- Indications d'application
- WB: 2-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Antigène
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- Autre désignation
- S100A8 (S100A8 Produits)
- Synonymes
- anticorps 60B8AG, anticorps CAGA, anticorps CFAG, anticorps CGLA, anticorps CP-10, anticorps L1Ag, anticorps MA387, anticorps MIF, anticorps MRP8, anticorps NIF, anticorps P8, anticorps Mrp8, anticorps S100A8, anticorps 60B8Ag, anticorps AI323541, anticorps B8Ag, anticorps CFAg, anticorps Caga, anticorps p8, anticorps MRP-8, anticorps S100 calcium binding protein A8, anticorps S100 calcium binding protein A8 (calgranulin A), anticorps S100A8, anticorps S100a8
- Sujet
- S100A8 is a low molecular weight (10 kDa) secreted cytoplasmic protein belonging to S100 family of calcium- and zinc-binding protein. S100A8 regulates a number of cellular processes, such as, inflammation, antimicrobial, oxidant-scavenging and apoptosis-inducing activities, cell cycle progression and differentiation, leukocyte arachidonic acid trafficking and metabolism. S100A8 is a homodimer but predominantly remains as heterodimer with S100A9 and the S100A8/S100A9 complex is called as Calprotectin. S100A8 is generally expressed in myeloid cells, neutrophils, monocytes and keratinocytes but high levels are found in the serum sample of patients with inflammatory diseases, such as, rheumatoid, cystic fibrosis, inflammatory bowel disease, systemic lupus erythematosus, progressive systemic sclerosis and many other inflammatory diseases. S100A8 is also associated with Psoriasis (an inflammatory skin disorder characterized by keratinocyte hyperproliferation and altered differentiation).
- Poids moléculaire
- 10 kDa
- ID gène
- 6279
- UniProt
- P05109
- Pathways
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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