CYP1B1 anticorps (AA 1-260)

N° du produit ABIN5027128

Détail du produit anti-CYP1B1 anticorps

Antigène: CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))

Épitope: AA 1-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP1B1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant CYP1B1 protein (amino acids 1-260) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur CYP1B1

Antigène: CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))

Autre désignation: CYP1B1 (CYP1B1 Produits)

Synonymes: anticorps CP1B, anticorps CYPIB1, anticorps GLC3A, anticorps P4501B1, anticorps P4501b1, anticorps CYP1B1, anticorps CYP1B, anticorps zgc:136223, anticorps cytochrome P450 family 1 subfamily B member 1, anticorps cytochrome P450, family 1, subfamily b, polypeptide 1, anticorps cytochrome P450, family 1, subfamily B, polypeptide 1, anticorps cytochrome P450 1B1, anticorps CYP1B1, anticorps Cyp1b1, anticorps cyp1b1, anticorps LOC100719054

Sujet: CYP1B1 (Cytochrome P450 1B1) belongs to the CYP450 superfamily of heme-binding mono-oxygenases which catalyze oxidation of various endogenous and exogenous substrates. The expression of Cyp1b1 plays an important role in the modulation of development and functions of the trabecular meshwork (TM). Mutations in Cyp1b1 found in patients with primary congenital glaucoma (PCG).It plays an important role in breast cancer development and progression by bioactivating endogenous estrogens and environmental carcinogens. It is over-expressed at the early stage of NNK-induced lung tumorigenesis.

Poids moléculaire: 62 kDa

ID gène: 1545

UniProt: Q16678

Pathways: Steroid Hormone Biosynthesis