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CD25 anticorps

IL2RA Reactivité: Humain FACS Hôte: Souris Monoclonal 7G7B6 unconjugated
N° du produit ABIN5027863
  • Antigène Voir toutes CD25 (IL2RA) Anticorps
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Reactivité
    • 182
    • 119
    • 38
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 146
    • 90
    • 78
    • 2
    • 1
    Souris
    Clonalité
    • 237
    • 76
    • 2
    Monoclonal
    Conjugué
    • 110
    • 32
    • 27
    • 27
    • 21
    • 11
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD25 est non-conjugé
    Application
    • 212
    • 91
    • 57
    • 50
    • 42
    • 36
    • 22
    • 16
    • 14
    • 14
    • 10
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    Protein G Chromatography
    Immunogène
    Recombinant human CD25 protein was used as an imunogen for this antidody.
    Clone
    7G7B6
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product IL2RA Anticorps primaire
  • Indications d'application
    FACS: 0.5-1 μg/10^6 cells
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Antigène
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Autre désignation
    hCD25 (IL2RA Produits)
    Synonymes
    anticorps CD25, anticorps IDDM10, anticorps IL2R, anticorps TCGFR, anticorps IL2RAC, anticorps IL-2RA, anticorps Il2r, anticorps Ly-43, anticorps interleukin 2 receptor subunit alpha, anticorps interleukin-2 receptor subunit alpha-like, anticorps interleukin 2 receptor, alpha chain, anticorps IL2RA, anticorps Il2ra, anticorps LOC100222957
    Sujet
    CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. Though CD25 has been shown to influence effector function of lymphocytes, it is thought to play a greater role in immune tolerance in mice. Constitutive expression of CD25 on Treg cells is thought to be crucial to their survival and maintenance of immune homeostasis. Expression of CD25 and its role in immunology may be species dependent, since CD25 appears to play a larger role in T-cell effector responses in humans compared to mice, and may be somewhat dispensable for the maintenance of Treg cells as seen in patients treated with CD25-blocking antibodies.
    ID gène
    3559
    UniProt
    P01589
    Pathways
    Signalistation JAK/STAT, Growth Factor Binding, Activated T Cell Proliferation
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