Angiopoietin 1 anticorps (C-Term)

N° du produit ABIN504734

Détail du produit anti-Angiopoietin 1 anticorps

Antigène: Angiopoietin 1 (ANGPT1)

Épitope: C-Term

Reactivité: Humain, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Chien, Humain, Lapin, Rat (Rattus)

Purification: affinity purified

Immunogène: C-terminal sequence of human Angiopoietin-1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: Angiopoietin-1 (ANGPT1 Produits)

Synonymes: anticorps AGP1, anticorps AGPT, anticorps ANG1, anticorps 1110046O21Rik, anticorps Ang-1, anticorps Ang1, anticorps Agpt, anticorps Agpt1, anticorps ang1, anticorps wu:fc76g06, anticorps ANG-1, anticorps angpt1, anticorps MGC80788, anticorps angiopoietin 1, anticorps angiopoietin 1 S homeolog, anticorps ANGPT1, anticorps Angpt1, anticorps angpt1, anticorps angpt1.S

Sujet: Angiopoietin 1 is one of the Angiopoietin (Ang) family of growth factors. It binds and activates the TIE2 receptor tyrosine kinase by inducing its tyrosine phosphorylation. It is implicated in endothelial developmental processes later and distinct from that of VEGF. The structure of angiopoietin 1 differs from that of known angiogenic factors or other ligands for receptor tyrosine kinases. Angiopoietin 1 appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. It also mediates blood vessel maturation/stability and it may play an important role in the heart early development. Angiopoietin 1 may have a potential therapeutic utility since it can be used for specifically targeting tumor vasculature or for promoting angiogenic processes in certain organs such as an ischemic heart.

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process