IRAK4 anticorps (pThr345)

N° du produit ABIN534253

Détail du produit anti-IRAK4 anticorps

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Épitope: pThr345

Reactivité: Humain, Souris, Boeuf (Vache), Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IRAK4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Dot Blot (DB)

Fonction: Mouse monoclonal antibody raised against synthetic phosphopeptide of IRAK4.

Séquence: VMTSR

Specificité: This antibody recognizes IRAK4 (phospho T345) with a phosphorylated site at Threonine 345. It does not cross-react with non-phosphospecific peptide.

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding T345 of human IRAK4.

Clone: A8A8

Isotype: IgG1

Information d'application

Indications d'application: Western Blot (0.1-1 μg/mL)
ELISA (0.01-0.1 μg/mL)
Immunoprecipitation (2-5 μg/mL)
Immunohistochemistry (2-5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In TBS, pH 7.2 (BSA, 10 % Proclin300)

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-IRAK4 (ABIN534253)

Lehmann, Krüger, Park, Derkow, Rosenberger, Baumgart, Trimbuch, Eom, Hinz, Kaul, Habbel, Kälin, Franzoni, Rybak, Nguyen, Veh, Ninnemann, Peters, Nitsch, Heppner, Golenbock, Schott, Ploegh, Wulczyn et al.: "An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ..." dans: Nature neuroscience, Vol. 15, Issue 6, pp. 827-35, (2012) (PubMed).

Srivastava, Geng, Liu, Zheng, Li, Joseph, McKenna, Bansal, Ochoa, Davila: "Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4." dans: Cancer research, Vol. 72, Issue 23, pp. 6209-16, (2012) (PubMed).

Li, Strelow, Fontana, Wesche: "IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5567-72, (2002) (PubMed).

Détails sur IRAK4

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Autre désignation: IRAK4 (IRAK4 Produits)

Synonymes: anticorps zgc:55553, anticorps IRAK4, anticorps ipd1, anticorps irak-4, anticorps ny-ran-64, anticorps ny-ren-64, anticorps ren64, anticorps irak4, anticorps IPD1, anticorps IRAK-4, anticorps NY-REN-64, anticorps REN64, anticorps 8430405M07Rik, anticorps 9330209D03Rik, anticorps interleukin 1 receptor associated kinase 4, anticorps interleukin-1 receptor-associated kinase 4, anticorps IRAK4, anticorps irak4, anticorps Irak4

ID gène: 51135

Pathways: Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades