Integrin Alpha2b anticorps (Biotin)

N° du produit ABIN536003

Détail du produit anti-Integrin Alpha2b anticorps (Biotin)

Antigène: Integrin Alpha2b (CD41)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin Alpha2b est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Fonction: Mouse monoclonal antibody raised against native ITGA2B.

Specificité: This antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 KDa) and GPIIb beta (light chain, 23 KDa). CD41 is mainly expressed on platelets and megakaryocytes.

Réactivité croisée: Humain

Immunogène: Native purified ITGA2B from leukocytes of a patient suffering from a LGL-type leukemia.

Clone: MEM-06

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry (1:200)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-Integrin Alpha2b (Biotin) (ABIN536003)

Zhang, Varas, Stadtfeld, Heck, Faust, Graf: "CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation." dans: Experimental hematology, Vol. 35, Issue 3, pp. 490-499, (2007) (PubMed).

Ferkowicz, Starr, Xie, Li, Johnson, Shelley, Morrison, Yoder: "CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo." dans: Development (Cambridge, England), Vol. 130, Issue 18, pp. 4393-403, (2003) (PubMed).

Mitjavila-Garcia, Cailleret, Godin, Nogueira, Cohen-Solal, Schiavon, Lecluse, Le Pesteur, Lagrue, Vainchenker: "Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells." dans: Development (Cambridge, England), Vol. 129, Issue 8, pp. 2003-13, (2002) (PubMed).

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: CD41 / ITGA2B (CD41 Produits)

Synonymes: anticorps AI172977, anticorps CD41, anticorps CD41B, anticorps GpIIb, anticorps alphaIIb, anticorps BDPLT16, anticorps BDPLT2, anticorps GP2B, anticorps GPIIb, anticorps GT, anticorps GTA, anticorps HPA3, anticorps integrin alpha 2b, anticorps integrin subunit alpha 2b, anticorps Itga2b, anticorps ITGA2B

ID gène: 3674

Pathways: Integrin Complex