p300 anticorps (E1A Binding Protein P300) (pSer89)

Details for Product anti-EP300 Antibody No. ABIN537611
Antigène
Épitope
pSer89
60
39
15
10
6
6
5
4
4
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
236
108
85
3
3
3
3
3
2
Hôte
Lapin
194
52
Clonalité
Polyclonal
Conjugué
Cet anticorp p300 est non-conjugé
12
9
9
6
6
6
5
5
5
5
5
5
2
2
2
2
2
Application
Dot Blot (DB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
151
114
87
50
46
35
28
20
11
5
4
3
3
3
2
1
1
Options
Fonction Rabbit polyclonal antibody raised against synthetic phosphopeptide of EP300.
Immunogène Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S89 of human EP300.
Antigène
Autre désignation EP300 / P300 (EP300 Antibody Extrait)
Pathways Signalisation p53, Signalisation Notch, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
Indications d'application Dot Blot (1:500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.09 % sodium azide)
Stock 4 °C,-20 °C
Stockage commentaire Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-E1A Binding Protein P300 (EP300) (pSer89) antibody (ABIN537611) Dot blot analysis of EP300 (phospho S89) polyclonal antibody on nitrocellulose membr...
Image no. 2 for anti-E1A Binding Protein P300 (EP300) (pSer89) antibody (ABIN537611) Formalin-fixed and paraffin-embedded human cancer tissue reacted with EP300 (phospho ...
Produit citée dans: Jin, Jeon, Li, Lee, Choi, Kim, Lee, Bae: "Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation." dans: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29409-17, 2004 (PubMed).

Finlan, Hupp: "The N-terminal interferon-binding domain (IBiD) homology domain of p300 binds to peptides with homology to the p53 transactivation domain." dans: The Journal of biological chemistry, Vol. 279, Issue 47, pp. 49395-405, 2004 (PubMed).

Dornan, Eckert, Wallace, Shimizu, Ramsay, Hupp, Ball: "Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53." dans: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10083-98, 2004 (PubMed).