ECT2 anticorps (pThr790)

N° du produit ABIN538145

Détail du produit anti-ECT2 anticorps

Antigène: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Épitope: pThr790

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Singe, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ECT2 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ECT2.

Specificité: Reactivity occurs against human ECT2 protein at the pT790 residue. By ELISA This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated human ECT2 is minimal by ELISA, but western blot shows specific staining of interphase cell lysates, which are predicted to contain non-phosphorylated ECT2.

Réactivité croisée: Poulet, Chimpanzé, Chien, Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding T790 of human ECT2.

Information d'application

Indications d'application: ELISA (1:10000-1:40000)
Western Blot (1:1000-1:4000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ECT2 (ABIN538145)

Niiya, Xie, Lee, Inoue, Miki: "Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner." dans: The Journal of biological chemistry, Vol. 280, Issue 43, pp. 36502-9, (2005) (PubMed).

Zhao, Fang: "MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13158-63, (2005) (PubMed).

Kim, Billadeau, Chen: "The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis." dans: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5733-9, (2005) (PubMed).

Détails sur ECT2

Antigène: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Autre désignation: ECT2 (ECT2 Produits)

Synonymes: anticorps ECT2, anticorps arhgef31, anticorps xect2, anticorps AI528536, anticorps mKIAA4037, anticorps ARHGEF31, anticorps ect2, anticorps epithelial cell transforming 2, anticorps ect2 oncogene, anticorps epithelial cell transforming 2 S homeolog, anticorps ECT2, anticorps ect2, anticorps Ect2, anticorps ect2.S

ID gène: 1894

Pathways: Neurotrophin Signaling Pathway, Cell-Cell Junction Organization