PERK anticorps (AA 601-1115)

N° du produit ABIN538307

Détail du produit anti-PERK anticorps

Antigène: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Épitope: AA 601-1115

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PERK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Fonction: Rabbit polyclonal antibody raised against partial recombinant Eif2ak3.

Réactivité croisée: Souris

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: Recombinant protein corresponding to amino acids 601-1115 of mouse Eif2ak3.

Information d'application

Indications d'application: Western Blot (1:500-1:3000)
Immunoprecipitation (10-30 µL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-PERK (ABIN538307)

Lee, Surh: "Nrf2 as a novel molecular target for chemoprevention." dans: Cancer letters, Vol. 224, Issue 2, pp. 171-84, (2005) (PubMed).

Cullinan, Zhang, Hannink, Arvisais, Kaufman, Diehl: "Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival." dans: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7198-209, (2003) (PubMed).

Ma, Vattem, Wek: "Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress." dans: The Journal of biological chemistry, Vol. 277, Issue 21, pp. 18728-35, (2002) (PubMed).

Détails sur PERK

Antigène: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Autre désignation: EIF2AK3 (EIF2AK3 Produits)

Synonymes: anticorps EIF2AK3, anticorps AI427929, anticorps Pek, anticorps Perk, anticorps PEK, anticorps PERK, anticorps WRS, anticorps eukaryotic translation initiation factor 2 alpha kinase 3, anticorps EIF2AK3, anticorps Eif2ak3

ID gène: 13666

Pathways: Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response