PRKDC anticorps (pThr2609)

N° du produit ABIN538467

Détail du produit anti-PRKDC anticorps

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Épitope: pThr2609

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKDC est non-conjugé

Application: ELISA, Western Blotting (WB)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKDC.

Specificité: This phospho-specific polyclonal antibody reacts with phosphorylated pT2609 of human DNA PKcs. Reactivity with non-phosphorylated human DNA PKcs is minimal.

Réactivité croisée: Poulet, Chimpanzé, Chien, Cheval, Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding T2609 of human PRKDC.

Information d'application

Indications d'application: ELISA (1:300000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-PRKDC (ABIN538467)

Panta, Kaur, Cavin, Cortés, Mercurio, Lothstein, Sweatman, Israel, Arsura et al.: "ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of ..." dans: Molecular and cellular biology, Vol. 24, Issue 5, pp. 1823-35, (2004) (PubMed).

Sawchuk, Mansilla-Soto, Alarcon, Singha, Langen, Bianchi, Lees-Miller, Nussenzweig, Cortes: "Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule." dans: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29821-31, (2004) (PubMed).

Graham, Gustin, Rivera, Kuyumcu-Martinez, Choe, Lloyd, Sarnow, Utz: "Proteolytic cleavage of the catalytic subunit of DNA-dependent protein kinase during poliovirus infection." dans: Journal of virology, Vol. 78, Issue 12, pp. 6313-21, (2004) (PubMed).

Détails sur PRKDC

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Autre désignation: DNA-PKcs / PRKDC / XRCC7 (PRKDC Produits)

Synonymes: anticorps DNA-PKcs, anticorps DNAPK, anticorps DNPK1, anticorps HYRC, anticorps HYRC1, anticorps XRCC7, anticorps p350, anticorps DNA-PKCS, anticorps dna-pkcs, anticorps dnapk, anticorps dnpk1, anticorps hyrc, anticorps hyrc1, anticorps prkdc-A, anticorps xrcc7, anticorps PRKDC, anticorps AI326420, anticorps AU019811, anticorps DNAPDcs, anticorps DOXNPH, anticorps dxnph, anticorps p460, anticorps scid, anticorps slip, anticorps protein kinase, DNA-activated, catalytic polypeptide, anticorps protein kinase, DNA-activated, catalytic polypeptide L homeolog, anticorps DNA-dependent protein kinase catalytic subunit, anticorps protein kinase, DNA activated, catalytic polypeptide, anticorps PRKDC, anticorps prkdc.L, anticorps LOC100633457, anticorps Prkdc

ID gène: 5591

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response