IL7R anticorps (pTyr449)

N° du produit ABIN538474

Détail du produit anti-IL7R anticorps

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Épitope: pTyr449

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL7R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of Il7r.

Specificité: This antibody is specific to mouse IL-7 protein phosphorylated at Y449.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding Y449 of mouse Il7r.

Information d'application

Indications d'application: ELISA (1:100000)
Western Blot (1:1000-1:10000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-IL7R (ABIN538474)

Osborne, Dhanji, Snow, Priatel, Ma, Miners, Teh, Goldsmith, Abraham: "Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice." dans: The Journal of experimental medicine, Vol. 204, Issue 3, pp. 619-31, (2007) (PubMed).

Hartigan-OConnor, Poon, Sinclair, McCune: "Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells." dans: Journal of immunological methods, Vol. 319, Issue 1-2, pp. 41-52, (2007) (PubMed).

Castellino, Germain: "Chemokine-guided CD4+ T cell help enhances generation of IL-6RalphahighIL-7Ralpha high prememory CD8+ T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 2, pp. 778-87, (2007) (PubMed).

Détails sur IL7R

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Autre désignation: CD127 / IL7R (IL7R Produits)

Synonymes: anticorps IL7R, anticorps CD127, anticorps IL-7Ralpha, anticorps CDW127, anticorps IL-7R-alpha, anticorps IL7RA, anticorps ILRA, anticorps IL-7RA, anticorps interleukin 7 receptor, anticorps IL7R, anticorps Il7r

ID gène: 16197

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size