EGLN1 anticorps (AA 350-426)

N° du produit ABIN540735

Détail du produit anti-EGLN1 anticorps

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Épitope: AA 350-426

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of EGLN1.

Specificité: This antibody is specific to human HIF prolyl hydroxylase 2. There is 83 % homology between the immunogen used for this antibody and the rat and mouse proteins.

Réactivité croisée: Humain

Immunogène: A synthetic peptide corresponding to amino acids 350-426 of human EGLN1.

Information d'application

Indications d'application: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.

Références pour anticorps anti-EGLN1 (ABIN540735)

Wong, Goehring, Kapiloff, Langeberg, Scott: "mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha." dans: Science signaling, Vol. 1, Issue 51, pp. ra18, (2008) (PubMed).

Colla, Tagliaferri, Morandi, Lunghi, Donofrio, Martorana, Mancini, Lazzaretti, Mazzera, Ravanetti, Bonomini, Ferrari, Miranda, Ladetto, Neri, Neri, Greco, Mangoni, Bonati, Rizzoli, Giuliani et al.: "The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha ..." dans: Blood, Vol. 110, Issue 13, pp. 4464-75, (2007) (PubMed).

Ietta, Wu, Winter, Xu, Wang, Post, Caniggia: "Dynamic HIF1A regulation during human placental development." dans: Biology of reproduction, Vol. 75, Issue 1, pp. 112-21, (2006) (PubMed).

Baek, Mahon, Oh, Kelly, Krishnamachary, Pearson, Chan, Giaccia, Semenza: "OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha." dans: Molecular cell, Vol. 17, Issue 4, pp. 503-12, (2005) (PubMed).

Détails sur EGLN1

Antigène: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Autre désignation: EGLN1 / PHD2 (EGLN1 Produits)

Synonymes: anticorps EGLN1, anticorps egln2, anticorps phd2, anticorps zgc:92314, anticorps AI503754, anticorps C1orf12, anticorps HIF-PH2, anticorps HPH-2, anticorps Hif-p4h-2, anticorps ORF13, anticorps Phd2, anticorps SM-20, anticorps PHD-2, anticorps PHD2, anticorps ECYT3, anticorps HIFPH2, anticorps HPH2, anticorps SM20, anticorps ZMYND6, anticorps egl nine homolog 1 (C. elegans), anticorps egl-9 family hypoxia inducible factor 1, anticorps egl-9 family hypoxia-inducible factor 1 S homeolog, anticorps egl-9 family hypoxia-inducible factor 1b, anticorps egl-9 family hypoxia-inducible factor 1, anticorps EGLN1, anticorps egln1.S, anticorps egln1b, anticorps Egln1

ID gène: 54583

Pathways: cAMP Metabolic Process, L'effet Warburg