PRKDC anticorps (pThr2609)

N° du produit ABIN542661

Détail du produit anti-PRKDC anticorps

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Épitope: pThr2609

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKDC est non-conjugé

Application: Dot Blot (DB)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of PRKDC.

Réactivité croisée: Humain

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T2609 of human PRKDC.

Information d'application

Indications d'application: Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-PRKDC (ABIN542661)

Ding, Reddy, Wang, Woods, Douglas, Ramsden, Lees-Miller, Meek: "Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair." dans: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5836-48, (2003) (PubMed).

Lucero, Gae, Taccioli: "Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response." dans: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 22136-43, (2003) (PubMed).

Goudelock, Jiang, Pereira, Russell, Sanchez: "Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex." dans: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 29940-7, (2003) (PubMed).

Détails sur PRKDC

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Autre désignation: DNA-PKcs / PRKDC / XRCC7 (PRKDC Produits)

Synonymes: anticorps DNA-PKcs, anticorps DNAPK, anticorps DNPK1, anticorps HYRC, anticorps HYRC1, anticorps XRCC7, anticorps p350, anticorps DNA-PKCS, anticorps dna-pkcs, anticorps dnapk, anticorps dnpk1, anticorps hyrc, anticorps hyrc1, anticorps prkdc-A, anticorps xrcc7, anticorps PRKDC, anticorps AI326420, anticorps AU019811, anticorps DNAPDcs, anticorps DOXNPH, anticorps dxnph, anticorps p460, anticorps scid, anticorps slip, anticorps protein kinase, DNA-activated, catalytic polypeptide, anticorps protein kinase, DNA-activated, catalytic polypeptide L homeolog, anticorps DNA-dependent protein kinase catalytic subunit, anticorps protein kinase, DNA activated, catalytic polypeptide, anticorps PRKDC, anticorps prkdc.L, anticorps LOC100633457, anticorps Prkdc

ID gène: 5591

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response