KIT anticorps (N-Term)

N° du produit ABIN544317

Détail du produit anti-KIT anticorps

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Épitope: N-Term

Reactivité: Humain, Singe, Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of KIT.

Réactivité croisée: Humain, Singe, Primate

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human KIT.

Information d'application

Indications d'application: Flow Cytometry (1:10-50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-KIT (ABIN544317)

Lennartsson, Wernstedt, Engström, Hellman, Rönnstrand: "Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk." dans: Experimental cell research, Vol. 288, Issue 1, pp. 110-8, (2003) (PubMed).

Wardelmann, Losen, Hans, Neidt, Speidel, Bierhoff, Heinicke, Pietsch, Büttner, Merkelbach-Bruse: "Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors." dans: International journal of cancer. Journal international du cancer, Vol. 106, Issue 6, pp. 887-95, (2003) (PubMed).

Sakuma, Sakurai, Oguni, Hironaka, Saito: "Alterations of the c-kit gene in testicular germ cell tumors." dans: Cancer science, Vol. 94, Issue 6, pp. 486-91, (2003) (PubMed).

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: CD117 / c-kit (KIT Produits)

Synonymes: anticorps C-Kit, anticorps CD117, anticorps PBT, anticorps SCFR, anticorps Bs, anticorps Fdc, anticorps Gsfsco1, anticorps Gsfsco5, anticorps Gsfsow3, anticorps SCO1, anticorps SCO5, anticorps SOW3, anticorps Ssm, anticorps Tr-kit, anticorps W, anticorps c-KIT, anticorps c-kit, anticorps MGF, anticorps KIT, anticorps C-KIT, anticorps kit, anticorps receptor, anticorps sparse, anticorps Xkl-1, anticorps kit-a, anticorps kit-b, anticorps kl1-A, anticorps krk1, anticorps pbt, anticorps scfr, anticorps KIT proto-oncogene receptor tyrosine kinase, anticorps v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a, anticorps KIT proto-oncogene receptor tyrosine kinase S homeolog, anticorps KIT, anticorps Kit, anticorps kita, anticorps kit, anticorps kit.S

ID gène: 3815

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity