PML anticorps

N° du produit ABIN545269

Détail du produit anti-PML anticorps

Antigène: PML (Promyelocytic Leukemia (PML))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PML est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of PML.

Séquence: PRKVIKMESE EGKEA

Specificité: This antibody recognize synthetic peptide (PRKVIKMESEEGKEA) containing a predicted sumoylation site of human PML.

Réactivité croisée: Humain

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to human PML.

Information d'application

Indications d'application: ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-PML (ABIN545269)

Kawai, Akira, Reed: "ZIP kinase triggers apoptosis from nuclear PML oncogenic domains." dans: Molecular and cellular biology, Vol. 23, Issue 17, pp. 6174-86, (2003) (PubMed).

Favre, Butticaz, Stevenson, Jongeneel, Telenti: "High frequency of alternative splicing of human genes participating in the HIV-1 life cycle: a model using TSG101, betaTrCP, PPIA, INI1, NAF1, and PML." dans: Journal of acquired immune deficiency syndromes (1999), Vol. 34, Issue 2, pp. 127-33, (2003) (PubMed).

Puccetti, Beissert, Güller, Li, Hoelzer, Ottmann, Ruthardt: "Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis." dans: Oncogene, Vol. 22, Issue 44, pp. 6900-8, (2003) (PubMed).

Détails sur PML

Antigène: PML (Promyelocytic Leukemia (PML))

Autre désignation: PML / RNF71 (PML Produits)

Synonymes: anticorps MYL, anticorps PP8675, anticorps RNF71, anticorps TRIM19, anticorps 1200009E24Rik, anticorps AI661194, anticorps Trim19, anticorps RGD1562602, anticorps PML, anticorps promyelocytic leukemia, anticorps PML, anticorps Pml

ID gène: 5371

Pathways: Signalisation p53, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus