DOK1 anticorps (pSer450)

N° du produit ABIN548455

Détail du produit anti-DOK1 anticorps

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Épitope: pSer450

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of DOK1.

Specificité: This sequence is conserved in Dok1 from rat (Ser-449) and mouse (Ser-451). The site is not conserved in other Dok family members.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S450 of human DOK1.

Information d'application

Indications d'application: ELISA (1:2000)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-DOK1 (ABIN548455)

Woodring, Meisenhelder, Johnson, Zhou, Field, Shah, Bladt, Pawson, Niki, Pandolfi, Wang, Hunter: "c-Abl phosphorylates Dok1 to promote filopodia during cell spreading." dans: The Journal of cell biology, Vol. 165, Issue 4, pp. 493-503, (2004) (PubMed).

Lee, Andrieu, Saltel, Destaing, Auclair, Pouchkine, Michelon, Salaun, Kobayashi, Jurdic, Kieff, Sylla: "IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 50, pp. 17416-21, (2004) (PubMed).

Kashige, Carpino, Kobayashi: "Tyrosine phosphorylation of p62dok by p210bcr-abl inhibits RasGAP activity." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 5, pp. 2093-8, (2000) (PubMed).

Détails sur DOK1

Antigène: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Autre désignation: DOK1 / p62 dok (DOK1 Produits)

Synonymes: anticorps P62DOK, anticorps Dok-1, anticorps AW557123, anticorps p62DOK, anticorps dok1, anticorps zgc:76914, anticorps docking protein 1, anticorps docking protein 1b, anticorps DOK1, anticorps Dok1, anticorps dok1b

ID gène: 1796