RAGE anticorps (Middle Region)

N° du produit ABIN548553

Détail du produit anti-RAGE anticorps

Antigène: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAGE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of AGER.

Specificité: The synthetic peptide of this antibody different from the mouse and rat sequence by two amino acids.

Réactivité croisée: Humain, Souris, Lapin, Rat

Immunogène: A synthetic peptide corresponding to amino acids at middle region of human AGER.

Isotype: IgG

Information d'application

Indications d'application: Western Blot (1 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from 0.9 mg NaCl, 0.2 mg Na₂HPO₄ (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RAGE (ABIN548553)

Bierhaus, Haslbeck, Humpert, Liliensiek, Dehmer, Morcos, Sayed, Andrassy, Schiekofer, Schneider, Schulz, Heuss, Neundörfer, Dierl, Huber, Tritschler, Schmidt, Schwaninger, Haering, Schleicher, Kasper et al.: "Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. ..." dans: The Journal of clinical investigation, Vol. 114, Issue 12, pp. 1741-51, (2004) (PubMed).

Chavakis, Bierhaus, Al-Fakhri, Schneider, Witte, Linn, Nagashima, Morser, Arnold, Preissner, Nawroth: "The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment." dans: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1507-15, (2003) (PubMed).

Taguchi, Blood, del Toro, Canet, Lee, Qu, Tanji, Lu, Lalla, Fu, Hofmann, Kislinger, Ingram, Lu, Tanaka, Hori, Ogawa, Stern, Schmidt: "Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases." dans: Nature, Vol. 405, Issue 6784, pp. 354-60, (2000) (PubMed).

Détails sur RAGE

Antigène: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Autre désignation: RAGE / AGER (AGER Produits)

Synonymes: anticorps RAGE, anticorps AGER, anticorps advanced glycosylation end-product specific receptor, anticorps advanced glycosylation end product-specific receptor, anticorps MAPK/MAK/MRK overlapping kinase, anticorps AGER, anticorps Ager, anticorps LOC719012

ID gène: 177

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins