ATP7B anticorps (Middle Region)

N° du produit ABIN5514518

Détail du produit anti-ATP7B anticorps

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP7B est non-conjugé

Application: Western Blotting (WB)

Séquence: IIMSTLTLVV WIVIGFIDFG VVQRYFPNPN KHISQTEVII RFAFQTSITV

Homologie: Dog: 82%, Guinea Pig: 82%, Horse: 82%, Human: 100%, Mouse: 91%, Rabbit: 92%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against ATP7B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ATP7B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATP7B

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Autre désignation: ATP7B (ATP7B Produits)

Synonymes: anticorps PWD, anticorps WC1, anticorps WD, anticorps WND, anticorps Atp7a, anticorps tx, anticorps Hts, anticorps PINA, anticorps Wd, anticorps ATP7B, anticorps ATPase copper transporting beta, anticorps ATPase, Cu++ transporting, beta polypeptide, anticorps ATPase, Cu++ transporting, beta polypeptide (Wilson disease), anticorps copper-transporting ATPase 2, anticorps ATP7B, anticorps Atp7b, anticorps atp7b, anticorps LOC592143

Sujet: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Alias Symbols: WD, PWD, WC1, WND

Protein Size: 676

ID gène: 540

NCBI Accession: NM_000053, NP_000044

UniProt: P35670

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process