ATP6V0A4 anticorps (Middle Region)

N° du produit ABIN5514546

Détail du produit anti-ATP6V0A4 anticorps

Antigène: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V0A4 est non-conjugé

Application: Western Blotting (WB)

Séquence: ADATRIKRAL EQGMELSGSS MAPIMTTVQS KTAPPTFNRT NKFTAGFQNI

Attributs du produit: This is a rabbit polyclonal antibody against ATP6V0A4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human ATP6V0A4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATP6V0A4

Antigène: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Autre désignation: ATP6V0A4 (ATP6V0A4 Produits)

Synonymes: anticorps A4, anticorps ATP6N1B, anticorps ATP6N2, anticorps RDRTA2, anticorps RTA1C, anticorps RTADR, anticorps STV1, anticorps VPH1, anticorps VPP2, anticorps Atp6n1b, anticorps a4, anticorps ATPase H+ transporting V0 subunit a4, anticorps ATPase, H+ transporting, lysosomal V0 subunit A4, anticorps ATP6V0A4, anticorps Atp6v0a4

Sujet: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.

Alias Symbols: ATP6V0A4, ATP6N1B, ATP6N2,

Protein Interaction Partner: UBC, PFKM,

Protein Size: 940

ID gène: 50617

UniProt: Q9HBG4

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport