PCGF2 anticorps (Middle Region)

N° du produit ABIN5514708

Détail du produit anti-PCGF2 anticorps

Antigène: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCGF2 est non-conjugé

Application: Western Blotting (WB)

Séquence: EQEKGALSDD EIVSLSIEFY EGARDRDEKK GPLENGDGDK EKTGVRFLRC

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PCGF2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCGF2

Antigène: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Autre désignation: PCGF2 (PCGF2 Produits)

Synonymes: anticorps ZNF144, anticorps PCGF2, anticorps MEL-18, anticorps RNF110, anticorps Mel18, anticorps Rnf110, anticorps Zfp144, anticorps mel-18, anticorps polycomb group ring finger 2, anticorps PCGF2, anticorps Pcgf2

Sujet: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Alias Symbols: MEL-18, RNF110, ZNF144,

Protein Size: 344

ID gène: 7703

NCBI Accession: NM_007144, NP_009075

UniProt: P35227

Pathways: Chromatin Binding