NR1H4 anticorps (N-Term)

N° du produit ABIN5514777

Détail du produit anti-NR1H4 anticorps

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1H4 est non-conjugé

Application: Western Blotting (WB)

Séquence: VAGPLGQNLE VEPYSQYSNV QFPQVQPQIS SSSYYSNLGF YPQQPEEWYS

Homologie: Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NR1H4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human NR1H4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NR1H4

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Autre désignation: NR1H4 (NR1H4 Produits)

Synonymes: anticorps zgc:110190, anticorps zgc:92742, anticorps NR1H4, anticorps BAR, anticorps FXR, anticorps HRR-1, anticorps HRR1, anticorps RIP14, anticorps AI957360, anticorps Fxr, anticorps Rxrip14, anticorps nuclear receptor subfamily 1, group H, member 5 S homeolog, anticorps nuclear receptor subfamily 1, group H, member 4, anticorps nuclear receptor subfamily 1 group H member 4, anticorps nr1h5.S, anticorps nr1h4, anticorps NR1H4, anticorps Nr1h4

Sujet: This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.

Alias Symbols: BAR, FXR, HRR1, HRR-1, RIP14

Protein Size: 270

ID gène: 9971

NCBI Accession: NM_001206977, NP_001193906

UniProt: Q96RI1

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process