MTA2 anticorps (C-Term)
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- Antigène Voir toutes MTA2 Anticorps
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MTA2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KDLVAQAPLK PKTPRGTKTP INRNQLSQNR GLGGIMVKRA YETMAGAGVP
- Attributs du produit
- This is a rabbit polyclonal antibody against MTA2. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MTA2
- Top Product
- Discover our top product MTA2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
- Autre désignation
- MTA2 (MTA2 Produits)
- Synonymes
- anticorps MTA1L1, anticorps PID, anticorps fd61b05, anticorps wu:fd61b05, anticorps wu:fi29g02, anticorps zgc:63487, anticorps pid, anticorps mta1l1, anticorps MTA2, anticorps DKFZp470E0911, anticorps AW550797, anticorps Mata1l1, anticorps Mta1l1, anticorps mmta2, anticorps metastasis associated 1 family member 2, anticorps metastasis associated 1 family, member 2, anticorps metastasis-associated gene family, member 2, anticorps metastasis associated 1 family member 2 L homeolog, anticorps MTA2, anticorps mta2, anticorps Mta2, anticorps mta2.L
- Sujet
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This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Alias Symbols: MTA2, MTA1L1, PID,
Protein Interaction Partner: vpr, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, ZBTB16, UBC, RARA, ZBTB1, RNF2, GPHN, HNRNPR, TRIM28, PPP4R1, ROCK2, SPAG9, POLR2C, POLR2A, MAP4, RPP25, LSM8, GET4, LARP7, CD2AP, NR3C1, MTOR, EHBP1L1, RABEP2, BRCC3, SMEK1, ZGPAT, HDAC1, HDAC2, CSNK1E, MTA3, UBE3
Protein Size: 668 - ID gène
- 9219
- NCBI Accession
- NP_004730
- UniProt
- O94776
- Pathways
- Chromatin Binding
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