anticorps CLECSF9, anticorps MINCLE, anticorps C86253, anticorps Clecsf9, anticorps Mincle, anticorps CLEC4E, anticorps C-type lectin domain family 4 member E, anticorps C-type lectin domain family 4, member e, anticorps C-type lectin domain family 4, member E, anticorps CLEC4E, anticorps Clec4e, anticorps LOC611538
Sujet
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.