SNAPIN anticorps (Middle Region)

N° du produit ABIN5516173

Détail du produit anti-SNAPIN anticorps

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAPIN est non-conjugé

Application: Western Blotting (WB)

Séquence: LDPYVKKLLN ARRRVVLVNN ILQNAQERLR RLNHSVAKET ARRRAMLDSG

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SNAPIN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNAPIN

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Autre désignation: SNAPIN (SNAPIN Produits)

Synonymes: anticorps SNAPAP, anticorps si:dkey-222b8.2, anticorps SNAPIN, anticorps BLOC1S7, anticorps BLOS7, anticorps 25kDa, anticorps AA407989, anticorps AV026596, anticorps Bloc1s7, anticorps Snap25bp, anticorps Snapap, anticorps SNAP associated protein, anticorps SNAP-associated protein L homeolog, anticorps SNAP-associated protein, anticorps SNAPIN, anticorps snapin.L, anticorps snapin, anticorps Snapin

Sujet: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Alias Symbols: BLOS7, SNAPAP, BLOC1S7,

Protein Size: 136

ID gène: 23557

NCBI Accession: NM_012437, NP_036569

UniProt: O95295

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis