CYP27B1 anticorps (C-Term)

N° du produit ABIN5516283

Détail du produit anti-CYP27B1 anticorps

Antigène: CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP27B1 est non-conjugé

Application: Western Blotting (WB)

Séquence: FRPARWLGEG PTPHPFASLP FGFGKRSCMG RRLAELELQM ALAQILTHFE

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP27B1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP27B1

Antigène: CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))

Autre désignation: CYP27B1 (CYP27B1 Produits)

Synonymes: anticorps cp2b, anticorps cyp1, anticorps cyp1alpha, anticorps cyp27b, anticorps p450c1, anticorps pddr, anticorps vdd1, anticorps vddr, anticorps vddri, anticorps vdr, anticorps CP2B, anticorps CYP1, anticorps CYP1alpha, anticorps CYP27B, anticorps P450c1, anticorps PDDR, anticorps VDD1, anticorps VDDR, anticorps VDDRI, anticorps VDR, anticorps Cyp40, anticorps Cp2b, anticorps Cyp1, anticorps Cyp27b, anticorps Pddr, anticorps Vdd1, anticorps Vddr, anticorps VddrI, anticorps Vdr, anticorps cytochrome P450 family 27 subfamily B member 1, anticorps cytochrome P450, family 27, subfamily B, polypeptide 1, anticorps cytochrome P450, family 27, subfamily b, polypeptide 1, anticorps cyp27b1, anticorps CYP27B1, anticorps Cyp27b1

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.

Alias Symbols: VDR, CP2B, CYP1, PDDR, VDD1, VDDR, VDDRI, CYP27B, P450c1, CYP1alpha

Protein Size: 508

ID gène: 1594

NCBI Accession: NM_000785, NP_000776

UniProt: O15528

Pathways: Metabolism of Steroid Hormones and Vitamin D