MBD4 anticorps (Middle Region)

N° du produit ABIN5516287

Détail du produit anti-MBD4 anticorps

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD4 est non-conjugé

Application: Western Blotting (WB)

Séquence: TSLKPEDFDF TVLSKRGIKS RYKDCSMAAL TSHLQNQSNN SNWNLRTRSK

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MBD4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MBD4

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Autre désignation: MBD4 (MBD4 Produits)

Synonymes: anticorps MED1, anticorps Med1, anticorps methyl-CpG binding domain 4, DNA glycosylase, anticorps methyl-CpG binding domain protein 4, anticorps methyl-CpG binding domain 4 DNA glycosylase, anticorps MBD4, anticorps Mbd4

Sujet: The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alias Symbols: MED1

Protein Size: 580

ID gène: 8930

NCBI Accession: NM_001276270, NP_001263199

UniProt: O95243

Pathways: Réparation de l'ADN