APC anticorps (Middle Region)

N° du produit ABIN5516442

Détail du produit anti-APC anticorps

Antigène: APC (Adenomatous Polyposis Coli (APC))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC est non-conjugé

Application: Western Blotting (WB)

Séquence: SETFDNIDNL SPKASHRSKQ RHKQSLYGDY VFDTNRHDDN RSDNFNTGNM

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human APC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur APC

Antigène: APC (Adenomatous Polyposis Coli (APC))

Autre désignation: APC (APC Produits)

Synonymes: anticorps dp2, anticorps dp3, anticorps fap, anticorps fpc, anticorps xapc, anticorps dp2.5, anticorps AI047805, anticorps AU020952, anticorps AW124434, anticorps CC1, anticorps Min, anticorps mAPC, anticorps BTPS2, anticorps DP2, anticorps DP2.5, anticorps DP3, anticorps GS, anticorps PPP1R46, anticorps RATAPC, anticorps APC1, anticorps APC, WNT signaling pathway regulator, anticorps adenomatous polyposis coli, anticorps adenomatous polyposis coli protein, putative, anticorps adenomatosis polyposis coli, anticorps adenomatous polyposis coli L homeolog, anticorps APC, anticorps apc, anticorps Smp_139190, anticorps Apc, anticorps apc.L

Sujet: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Alias Symbols: GS, DP2, DP3, BTPS2, DP2.5, PPP1R46

Protein Size: 1304

ID gène: 324

NCBI Accession: NM_000038, NP_000029

UniProt: E9PFT7

Pathways: Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization