Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Phospholipase C gamma 1 anticorps (C-Term)

PLCG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5517384
  • Antigène Voir toutes Phospholipase C gamma 1 (PLCG1) Anticorps
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Épitope
    • 42
    • 28
    • 14
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 156
    • 140
    • 130
    • 23
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye
    Hôte
    • 159
    • 29
    Lapin
    Clonalité
    • 143
    • 45
    Polyclonal
    Conjugué
    • 87
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Cet anticorp Phospholipase C gamma 1 est non-conjugé
    Application
    • 122
    • 53
    • 38
    • 33
    • 28
    • 27
    • 19
    • 18
    • 15
    • 15
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    RGIVCPFVEI EVAGAEYDST KQKTEFVVDN GLNPVWPAKP FHFQISNPEF
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PLCG1. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human PLCG1
    Top Product
    Discover our top product PLCG1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Autre désignation
    PLCG1 (PLCG1 Produits)
    Synonymes
    anticorps NCKAP3, anticorps PLC-II, anticorps PLC1, anticorps PLC148, anticorps PLCgamma1, anticorps plc1, anticorps nckap3, anticorps plc-ii, anticorps plc148, anticorps plcgamma1, anticorps PPLCA, anticorps AI894140, anticorps Cded, anticorps Plc-1, anticorps Plc-gamma1, anticorps Plcg-1, anticorps fj46f04, anticorps wu:fj46f04, anticorps wu:fj57a05, anticorps phospholipase C gamma 1, anticorps phospholipase C gamma 1 L homeolog, anticorps 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, anticorps phospholipase C, gamma 1, anticorps PLCG1, anticorps plcg1.L, anticorps LOC100633163, anticorps Plcg1, anticorps plcg1
    Sujet
    The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PLC1

    Protein Interaction Partner: EGFR, UBC, SARNP, WDR61, RIC8A, AASDHPPT, UBR7, EHD4, DPP7, GTF3C4, LIMD1, RPL38, PYGB, ZAP70, KHDRBS1, RASA1, JAK2, JAK1, LCP2, ERBB3, ERBB2, CBL, LAT, VAV1, PDGFRB, INSR, IRS2, NTMT1, SPRY1, NPM1, NCAM1, ALK, PML, IBTK, EEF1A1, BLNK, BAG3, EPOR, CAMK2A,

    Protein Size: 1290
    ID gène
    5335
    UniProt
    P19174
    Pathways
    Signalisation RTK, Signalisation WNT, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
Vous êtes ici:
Support technique