NFATC1 anticorps (AA 589-652)

N° du produit ABIN5519043

Détail du produit anti-NFATC1 anticorps

Antigène: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Épitope: AA 589-652

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFATC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit IgG polyclonal antibody for NFAT2 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for NFAT2 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: nuclear factor of activated T-cells 1
Protein Name: Nuclear factor of activated T-cells, cytoplasmic 1

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived huamn NFAT2 recombinant protein (Position: Q589-K652).

Isotype: IgG

Information d'application

Indications d'application: Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur NFATC1

Antigène: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Autre désignation: NFATC1 (NFATC1 Produits)

Synonymes: anticorps nf-atc, anticorps nfat2, anticorps nfatc, anticorps si:ch211-198c22.2, anticorps NFATC1, anticorps 2210017P03Rik, anticorps AI449492, anticorps AV076380, anticorps NF-ATc, anticorps NFAT2, anticorps NFATc, anticorps Nfatcb, anticorps NF-ATC, anticorps NF-ATc1, anticorps NFAT, anticorps NFATmac, anticorps nuclear factor of activated T-cells 1, anticorps nuclear factor of activated T-cells 1 L homeolog, anticorps nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, anticorps NFATC1, anticorps nfatc1.L, anticorps nfatc1, anticorps Nfatc1

Sujet: NFATC1(Nuclear factor of activated T-cells, cytoplasmic 1), also known as NFATC or NFAT2, is a protein that in humans is encoded by the NFATC1 gene. And it is also a component of the nuclear factor of activated T cells DNA-binding transcription complex. The NFATC1 gene is mapped on 18q23. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. NFATC1 was not detected in brain, liver, or kidney. NFATC1 is an inducible nuclear component which functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. The solution structure of the binary complex formed between the core DNA-binding domain of human NFATC1 and the 12-bp oligonucleotide duplex containing the ARRE2 DNA site from the IL2 promoter. Nfatc1 was expressed exclusively in mouse hair follicle stem cells, and using gain- and loss-of-function approaches, and Nfatc1 inhibited stem cell activation.

Synonyms: Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2, NFATC

ID gène: 4772

UniProt: O95644

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway