CDK8 anticorps (AA 249-277)

N° du produit ABIN5532871

Détail du produit anti-CDK8 anticorps

Antigène: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Épitope: AA 249-277

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK8 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This CDK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human CDK8.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CDK8

Antigène: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Autre désignation: CDK8 (CDK8 Produits)

Synonymes: anticorps K35, anticorps wu:fk95h11, anticorps cyclin dependent kinase 8, anticorps cyclin-dependent kinase 8, anticorps cyclin-dependent kinase 8 S homeolog, anticorps Cyclin-dependent kinase 8, anticorps cyclin dependent kinase 19, anticorps CDK8, anticorps Cdk8, anticorps cdk8, anticorps cdk8.S, anticorps cdk-8, anticorps CDK19

Sujet: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.

Poids moléculaire: 53 kDa

ID gène: 1024

UniProt: P49336

Pathways: Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha