Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ACVRL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-44amino acids from the N-terminal region of human ACVRL1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
ACVRL1
(Activin A Receptor Type II-Like 1 (ACVRL1))
anticorps ACVRL1, anticorps vgb, anticorps alk1, anticorps zehn1109, anticorps hm:zehn1109, anticorps ACVRLK1, anticorps ALK-1, anticorps ALK1, anticorps HHT, anticorps HHT2, anticorps ORW2, anticorps SKR3, anticorps TSR-I, anticorps R-3, anticorps R3, anticorps SETHKIR, anticorps AI115505, anticorps AI427544, anticorps Acvrlk1, anticorps Alk1, anticorps activin A receptor like type 1, anticorps activin A receptor type II-like 1, anticorps activin A receptor, type II-like 1, anticorps ACVRL1, anticorps acvrl1, anticorps Acvrl1
Sujet
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.